Should RT‐PCR be considered a gold standard in the diagnosis of COVID‐19?

Autor: Eduardo Pérez-Campos Mayoral, Gabriel Mayoral-Andrade, Luis Manuel Sánchez Navarro, Edgar Zenteno, Laura Pérez-Campos Mayoral, Eduardo Pérez-Campos, María Teresa Hernández-Huerta
Přispěvatelé: Centre Hospitalier Universitaire de Martinique [Fort-de-France, Martinique], Centre Hospitalier Universitaire de Reims (CHU Reims), Vieillissement, Fragilité (VIEFRA - EA 3797), Université de Reims Champagne-Ardenne (URCA), Service de Médecine interne, Maladies Infectieuses et Immunologie Clinique [Reims], Département de Gériatrie [CHU Martinique], CHU de la Martinique [Fort de France]
Rok vydání: 2020
Předmět:
Pediatrics
RT‐PCR
Epidemiology
Disease
030218 nuclear medicine & medical imaging
law.invention
0302 clinical medicine
[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
law
Diagnosis
Pandemic
030212 general & internal medicine
Letter to the Editor
Biostatistics & Bioinformatics
Polymerase chain reaction
Covid‐19
[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases
education.field_of_study
Reverse Transcriptase Polymerase Chain Reaction
Gold standard
Reference Standards
3. Good health
Serology
Infectious Diseases
Real-time polymerase chain reaction
030220 oncology & carcinogenesis
COVID-19 Nucleic Acid Testing
030211 gastroenterology & hepatology
Covid-19
2019-20 coronavirus outbreak
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Population
RT-PCR
Sensitivity and Specificity
COVID-19 Serological Testing
03 medical and health sciences
Virology
medicine
Humans
education
Reference standards
Virus classification
SARS-CoV-2
business.industry
Gold standard (test)
Reverse transcriptase
Coronavirus
business
Zdroj: Journal of Medical Virology
Journal of Medical Virology, Wiley-Blackwell, 2020, ⟨10.1002/jmv.25996⟩
ISSN: 1096-9071
0146-6615
DOI: 10.1002/jmv.25996
Popis: International audience; To face the new Covid-19 pandemic, the need for early and accurate diagnosis of the disease among suspected cases quickly became obvious for effective management, and for better control of the spread of the disease in the population. Since the beginning of this disease epidemic caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), reverse transcriptase polymerase chain reaction (RT-PCR) has routinely been used to confirm diagnosis. However, several authors have pointed out the poor performance of this technique, particularly in terms of sensitivity.1,2 This article is protected by copyright. All rights reserved.
Databáze: OpenAIRE
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