Farm productive contexts and the dynamics of bovine viral diarrhea (BVD) transmission
| Autor: | Vittoria Colizza, Bryan Iotti, Armando Giovannini, Sergio Rosati, Mario Giacobini, Lara Savini, Eugenio Valdano, Luca Candeloro |
|---|---|
| Přispěvatelé: | University of Turin, Departament d'Enginyeria Informàtica i Matemàtiques, Universitat Rovira i Virgili, Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche (IZSUM), Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| Rok vydání: | 2019 |
| Předmět: |
Male
BVD Cattle trade movements Metapopulation model Productive classes Targeted intervention Animals Bovine Virus Diarrhea-Mucosal Disease Cattle Dairying Female Italy Models Statistical Animal Husbandry Diarrhea Viruses Bovine Viral 040301 veterinary sciences [SDV]Life Sciences [q-bio] 030231 tropical medicine Metapopulation Disease Biology law.invention 0403 veterinary science 03 medical and health sciences 0302 clinical medicine Food Animals Models law Diarrhea Viruses Seroprevalence Socioeconomics Viral diarrhea 2. Zero hunger 04 agricultural and veterinary sciences Statistical Transmission (mechanics) Scale (social sciences) Herd Bovine Viral Animal Science and Zoology Viral disease |
| Zdroj: | Preventive Veterinary Medicine Preventive Veterinary Medicine, Elsevier, 2019, 165, pp.23-33. ⟨10.1016/j.prevetmed.2019.02.001⟩ |
| ISSN: | 0167-5877 |
| DOI: | 10.1016/j.prevetmed.2019.02.001 |
| Popis: | Bovine viral diarrhea (BVD) is a viral disease that affects cattle and that is endemic to many European countries. It has a markedly negative impact on the economy, through reduced milk production, abortions, and a shorter lifespan of the infected animals. Cows becoming infected during gestation may give birth to Persistently Infected (PI) calves, which remain highly infective throughout their life, due to the lack of immune response to the virus. As a result, they are the key driver of the persistence of the disease both at herd scale, and at the national level. In the latter case, the trade-driven movements of PIs, or gestating cows carrying PIs, are responsible for the spatial dispersion of BVD. Past modeling approaches to BVD transmission have either focused on within-herd or between-herd transmission. A comprehensive portrayal, however, targeting both the generation of PIs within a herd, and their displacement throughout the country due to trade transactions, is still missing. We overcome this by designing a multiscale metapopulation model of the spatial transmission of BVD, accounting for both within-herd infection dynamics, and its spatial dispersion. We focus on Italy, a country where BVD is endemic and seroprevalence is very high. By integrating simple within-herd dynamics of PI generation, and the highly-resolved cattle movement dataset available, our model requires minimal arbitrary assumptions on its parameterization. We use our model to study the role of the different productive contexts of the Italian market, and test possible intervention strategies aimed at prevalence reduction. We find that dairy farms are the main drivers of BVD persistence in Italy, and any control strategy targeting these farms would lead to significantly higher prevalence reduction, with respect to targeting other production compartments. Our multiscale metapopulation model is a simple yet effective tool for studying BVD dispersion and persistence at country level, and is a good instrument for testing targeted strategies aimed at the containment or elimination of this disease. Furthermore, it can readily be applied to any national market for which cattle movement data is available. |
| Databáze: | OpenAIRE |
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