Performance characterization of a rotary centrifugal left ventricular assist device with magnetic suspension
| Autor: | Tigran Khalapyan, William E. Pae, Branka Lukic, Said Jahanmir, Andrew Z. Hunsberger, Hooshang Heshmat, William J. Weiss, Conrad M. Zapanta, James F. Walton, Michael J. Tomaszewski |
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| Rok vydání: | 2008 |
| Předmět: |
Glycerol
Male Materials science Rotation medicine.medical_treatment Biomedical Engineering Pulsatile flow Medicine (miscellaneous) Magnetic bearing Bioengineering Biocompatible Materials Blood Pressure Prosthesis Design Hemolysis Vibration law.invention Body Temperature Biomaterials law Biomimetic Materials Materials Testing medicine Alloys Animals Heart-Assist Devices Titanium Viscosity Water General Medicine equipment and supplies medicine.disease Blood pump Thrust bearing Ventricular assist device Heart failure Pulsatile Flow Models Animal Cattle Equipment Failure Electromagnetic Phenomena Biomedical engineering Destination therapy |
| Zdroj: | Artificial organs. 32(5) |
| ISSN: | 1525-1594 |
| Popis: | The MiTiHeart (MiTiHeart Corporation, Gaithersburg, MD, USA) left ventricular assist device (LVAD), a third-generation blood pump, is being developed for destination therapy for adult heart failure patients of small to medium frame that are not being served by present pulsatile devices. The pump design is based on a novel, patented, hybrid passive/active magnetic bearing system with backup hydrodynamic thrust bearing and exhibits low power loss, low vibration, and low hemolysis. Performance of the titanium alloy prototype was evaluated in a series of in vitro tests with blood analogue to map out the performance envelop of the pump. The LVAD prototype was implanted in a calf animal model, and the in vivo pump performance was evaluated. The animal's native heart imparted a strong pulsatility to the flow rate. These tests confirmed the efficacy of the MiTiHeart LVAD design and confirmed that the pulsatility does not adversely affect the pump performance. |
| Databáze: | OpenAIRE |
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