Feasibility and acceptability of continuous postoperative pericardial flushing for blood loss reduction in patients undergoing coronary artery bypass grafting
| Autor: | Hakan Kara, Tuncay Erden |
|---|---|
| Přispěvatelé: | Giresun Üniversitesi |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Blood transfusion Turkey medicine.medical_treatment Hemorrhage Pilot Projects 030204 cardiovascular system & hematology law.invention Coronary artery bypass grafting surgery 03 medical and health sciences Coronary artery bypass surgery 0302 clinical medicine Randomized controlled trial law Cardiac tamponade medicine Humans Blood Transfusion Postoperative hemorrhage Postoperative Period Prospective Studies Coronary Artery Bypass Chest tube Blood Coagulation Aged Retrospective Studies Aged 80 and over business.industry General Medicine Middle Aged medicine.disease Cardiac surgery Surgery medicine.anatomical_structure 030228 respiratory system Cardiothoracic surgery Feasibility Studies Female Cardiology and Cardiovascular Medicine business Continuous postoperative pericardial flushing Pericardium Platelet Aggregation Inhibitors Artery |
| ISSN: | 0005-1500 |
| Popis: | WOS: 000515006000002 PubMed: 31325107 Introduction Postoperative bleeding requires blood transfusion and surgical re-exploration that can affect the short- and long-term postoperative outcomes. Interventions that can be used in the postoperative period to reduce blood loss should be developed. Continuous postoperative pericardial flushing (CPPF) with an irrigation solution may reduce blood loss by preventing the accumulation of clots. This study examined the feasibility and acceptability of CPPF for reducing bleeding after coronary artery bypass surgery. Methods This pilot study adopted a prospective and group comparison design. Between January and April 2018, 42 patients who underwent isolated coronary artery bypass surgery received CPPF from sternal closure up to 8 h postoperative. The mean actual blood loss in the CPPF group was compared to the mean of retrospectively group (n = 58). In the CPPF group, an extra infusion catheter was inserted through one of the tube incision holes and an irrigation solution (0.9% NaCl at 38 degrees C) was delivered to the pericardial cavity by using a volumetric pump. Safety aspects, feasibility issues, and complications were documented. The primary outcome was blood loss, and it was assessed 18 h after the surgery. Results CPPF was successfully completed in 40 patients (95.24%). Method-related complications were not observed. Feasibility was good in this experimental setting. Blood loss was lower in the CPPF group (257.24 mL) than non-CPPF group (p < 0.001). Conclusions CPPF after coronary artery bypass grafting surgery is safe, effective, feasible, and acceptable. However, standardized randomized clinical trials are necessary to draw definitive conclusions. |
| Databáze: | OpenAIRE |
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