Laboratory Studies in Cross-Species Lung Transplantation
| Autor: | J. H. Burack, Stephen P. Squinto, M Vaynblatt, Lawson N, S L Kamholz, M. J. Del Rio, Allen J. Norin, Grijalva Ga, W L Fodor, R. J. Brewer |
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| Rok vydání: | 1997 |
| Předmět: |
medicine.medical_specialty
Swine Xenotransplantation medicine.medical_treatment Transplantation Heterologous CD59 Antigens Animals Genetically Modified medicine Animals Humans Lung transplantation Intensive care medicine Lung business.industry Graft Survival Donor lungs Surgery Transplantation Disease Models Animal medicine.anatomical_structure Ethical concerns Graft survival Respiratory Insufficiency business Lung Transplantation Papio |
| Zdroj: | World Journal of Surgery. 21:951-955 |
| ISSN: | 1432-2323 0364-2313 |
| DOI: | 10.1007/s002689900332 |
| Popis: | The lack of sufficient suitable human donor lungs for the many patients requiring pulmonary transplantation as life-saving therapy for end-stage lung diseases has generated extensive interest in cross-species lung transplantation. Ethical concerns and those of animal rights advocates have prompted studies of nonprimate species as potential solid organ donors for humans. This paper provides an overview of some of the laboratory studies of cross-species pulmonary transplantation performed over the past 20 years and focuses, in particular, on more recent work (from our laboratory and others) in the area of porcine-to-primate pulmonary xenotransplantation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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