Reconstruction of the orbital floor using supercritical CO2 decellularized porcine bone graft
| Autor: | Periasamy Srinivasan, Chao-Hsin Huang, Su-Shin Lee, Ying-Che Chen, Dar-Jen Hsieh, Yi-Chia Wu, Hsiao-Chen Lee, Ko-Chung Yen |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Swine bone graft Taiwan Enophthalmos Surgical Flaps supercritical carbon dioxide Porcine bone Animals Humans Medicine Outpatient clinic Complication rate Orbital Fractures Aged Retrospective Studies Diplopia Bone Transplantation Decellularization business.industry Decellularized Extracellular Matrix orbital wall reconstruction General Medicine Carbon Dioxide Middle Aged Plastic Surgery Procedures Infection rate Surgery Treatment Outcome xenogenic graft ABCcolla® collagen bone graft Heterografts Female Tomography medicine.symptom business Orbit Research Paper |
| Zdroj: | International Journal of Medical Sciences |
| ISSN: | 1449-1907 |
| DOI: | 10.7150/ijms.64359 |
| Popis: | Orbital floor fractures subsequently lead to consequences such as diplopia and enophthalmos. The graft materials used in orbital floor fractures varied from autografts to alloplastic grafts, which possess certain limitations. In the present study, a novel porcine bone matrix decellularized by supercritical CO2 (scCO2), ABCcolla® Collagen Bone Graft, was used for the reconstruction of the orbital framework. The study was approved by the institutional review board (IRB) of Kaohsiung Medical University Chung-Ho Memorial Hospital (KMUH). Ten cases underwent orbital floor reconstruction in KMUH in 2019. The orbital defects were fixed by the implantation of the ABCcolla® Collagen Bone Graft. Nine out of ten cases used 1 piece of customized ABCcolla® Collagen Bone Graft in each defect. The other case used 2 pieces of customized ABCcolla® Collagen Bone Graft in one defect area due to the curved outline of the defect. In the outpatient clinic, all 10 cases showed improvement of enophthalmos on CT (computerized tomography) at week 8 follow-up. No replacement of implants was needed during follow-ups. To conclude, ABCcolla® Collagen Bone Graft proved to be safe and effective in the reconstruction of the orbital floor with high accessibility, high stability, good biocompatibility, low infection rate and low complication rate. |
| Databáze: | OpenAIRE |
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