Effect of cereal-thickened formula and upright positioning on regurgitation, gastric emptying, and weight gain in infants with regurgitation
| Autor: | Yvan Vandenplas, Hsun-Chin Chao |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Endocrinology Diabetes and Metabolism Posture Weight Gain Gastroenterology Group B Internal medicine medicine Humans Prospective Studies Prospective cohort study Nutrition and Dietetics Gastric emptying Viscosity business.industry Stomach Infant Infant Formula Surgery Postprandial medicine.anatomical_structure Gastric Emptying Regurgitation (digestion) Gastroesophageal Reflux Vomiting Female medicine.symptom Edible Grain Energy Intake business Weight gain |
| Zdroj: | Nutrition. 23:23-28 |
| ISSN: | 0899-9007 |
| DOI: | 10.1016/j.nut.2006.10.003 |
| Popis: | We compared the effect of cereal-thickened formula or postural therapy on regurgitation and gastroesophageal reflux, weight gain, and gastric emptying in infants.We performed a prospective trial in exclusively formula-fed infants 2 to 6 mo of age presenting with regurgitation or vomiting at least three times a day. Infants were randomized into two groups; group A received cereal-thickened formula versus group B who were placed in a postprandial upright position for 90 min and evaluated over an 8-wk period. A 90-min technetium 99m milk scintigraphy was performed before and at the end of the intervention period.Thirty-one infants were included in group A and 32 in group B; at inclusion, there were no anthropometric differences between groups (P = 0.813-0.955). After 4 and 8 wk, the difference in regurgitation frequency per day between groups A and B had become significant (at 4 wk, 2.39 +/- 0.86 for group A versus 2.84 +/- 0.81 for group B, P = 0.039; at 8 wk, 1.61 +/- 0.76 for group A versus 2.38 +/- 0.83 for group B, P0.001). The volume ingested per meal was not different between groups after 4 wk, although this parameter showed a larger intake in group A after 8 wk (156.8 +/- 23.5 mL for group A versus 143.4 +/- 25.1 mL for group B, P = 0.035), resulting in a significant difference in mean caloric intake. Gastric emptying after 8 wk showed no significant difference between groups A and B. Group A infants had significantly greater weight gain than did group B infants after 4 wk (636.2 +/- 103.4 g for group A versus 577.4 +/- 102.7 g for group B, P = 0.03) and 8 wk (1261.3 +/- 131.4 g for group A versus 1121.4 +/- 137.2 g for group B, P0.001). After 8 wk of intervention, the increase in length was significantly greater in group A than in group B (5.2 +/- 0.6 cm for group A versus 4.7 +/- 0.6 cm for group B, P = 0.032).Cereal-thickened formula is significantly more efficacious than postural therapy in decreasing the frequency of regurgitation in regurgitating infants. Treatment of regurgitation with cereal-thickened formula results in an increased caloric intake ( approximately 25%), related to increased gain in weight and length, in comparison with regular formula and positioning therapy. |
| Databáze: | OpenAIRE |
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