The 1st International standard for transforming growth factor-β3 (TGF-β3)
| Autor: | Guoping Wu, Gao Kai, David Bending, Anne Cooke, John A Little, Chris Bird, Robin Thorpe, David Bender, Weihong Wang, Michelle Hamill, Paula Dilger, Tony Wyss-Coray, Katherine M. Getliffe, Alan B Heath, Meenu Wadhwa, Jo Read, Hui Zhang, Sarah Gibbs |
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| Rok vydání: | 2012 |
| Předmět: |
Immunoassay
Transforming Growth Factor beta3 medicine.diagnostic_test Computer science business.industry International standard Immunology Reference Standards Expert committee Biotechnology Human sequence medicine Humans Immunology and Allergy Biological Assay business Reference standards Transforming growth factor |
| Zdroj: | Journal of Immunological Methods. 380:1-9 |
| ISSN: | 0022-1759 |
| Popis: | One candidate preparation of human sequence recombinant transforming growth factor-β3 (TGF-β3) was formulated and lyophilized at NIBSC prior to evaluation in a collaborative study for its suitability to serve as an international standard. The preparation was tested by 8 laboratories using in vitro bioassays and immunoassays. The candidate preparation 09/234 was judged suitable to serve as an international standard based on the data obtained for biological activity and stability. On the basis of the results reported here, the preparation coded 09/234 was established by the WHO Expert Committee on Biological Standardisation (ECBS) as the WHO 1st IS for human TGF-β3 with an assigned value for TGF-β3 activity of 19,000 IU/ampoule. |
| Databáze: | OpenAIRE |
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