Sarcopenia: The need to establish different cutoff points of fat-free mass for the Chilean population

Autor: Gladys Barrera, María Pía de la Maza, Daniel Bunout, Sabrina Wigodski, Sandra Hirsch, Fernando Carrasco
Rok vydání: 2019
Předmět:
Zdroj: Nutrition. 57:217-224
ISSN: 0899-9007
DOI: 10.1016/j.nut.2018.05.031
Popis: Objectives International cutoff points for the diagnosis of sarcopenia are not applicable to the Chilean population due to previous evidence of a lower lean mass and strength in this population. Dual-energy x-ray absorptiometry is used to establish fat-free mass cutoff points to define sarcopenia in the Chilean population and analyze its association with handgrip strength in older adults. Methods Appendicular fat-free mass (AFFM) was calculated from 4062 dual-energy x-ray absorptiometries of healthy Chileans, ages 18 to 99 y. Possible cutoff points for sarcopenia were obtained using four methods: A) Normative, –2 standard deviation (SD) below mean AFFM/height2 (AFFMI) of adults age Results Using the normative method, sarcopenia was defined as an AFFMI Conclusions The AFFM of young Chileans is lower than that reported in Western countries but similar to Latin American data; therefore, the use of the traditional normative method would not be appropriate with –2 SD to establish cutoff points, and using –1 DS resulted in values that are higher than Baumgartner's. Stratification is advantageous because this method throws expected values of AFFM for each population; however, overdiagnosis of sarcopenia is a possibility and thus the method requires a representative sample. The percentage method is simple and showed the expected decrease of muscle mass with age, and also correlated well with handgrip strength in elderly women. Thus, this method represented our method of choice to detect sarcopenia.
Databáze: OpenAIRE