Interval training induces clinically meaningful effects in daily activity levels in COPD
| Autor: | Maroula Vasilopoulou, Ioannis Nasis, Stavroula Spetsioti, Ioannis Vogiatzis, Zafeiris Louvaris, Nikolaos Koulouris, Georgios Kaltsakas, Eleni Kortianou |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Activities of daily living Treatment outcome Pulmonary disease B300 High-Intensity Interval Training Interval training law.invention Pulmonary Disease Chronic Obstructive 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Internal medicine Activities of Daily Living medicine Humans Muscle Strength 030212 general & internal medicine Cardiac Output Aged COPD Exercise Tolerance business.industry Middle Aged medicine.disease C600 Treatment Outcome 030228 respiratory system Physical therapy Muscle strength Female business High-intensity interval training |
| Zdroj: | European Respiratory Journal. 48:567-570 |
| ISSN: | 1399-3003 0903-1936 |
| Popis: | Mounting evidence suggests that daily activity levels (DAL) in patients with chronic obstructive pulmonary disease (COPD) are markedly low compared with healthy age-matched individuals and are associated with poorer health status and prognosis [1]. COPD severity negatively impacts on DAL since patients with low DAL experience greater ventilatory, central haemodynamic and peripheral muscle oxygenation constraints during activities of daily living when compared with more physically active counterparts [2, 3]. Although exercise training as part of pulmonary rehabilitation has shown to mitigate the aforementioned physiological constraints [4], there is no evidence of clinically meaningful improvements in DAL following pulmonary rehabilitation [5] as manifested by a mean increase of at least 1000 steps·day−1 [6]. This has been attributed to methodological shortfalls, such as lack of adequately controlled studies, small sample size, short duration of pulmonary rehabilitation programmes, application of activity monitors non-validated for COPD patients [5] and insufficient exercise intensities to induce true physiological training effects. Interval exercise training has been shown to allow application of intense loads to peripheral muscles that induce substantial physiological effects manifested by mitigation of respiratory and central haemodynamic limitations and partial restoration of peripheral muscle dysfunction in patients with diverse COPD severity [7, 8]. In this context, it is reasoned that application of this training modality would allow transfer of the aforementioned physiological benefits into clinically meaningful improvements in DAL [2, 3]. Accordingly, the purpose of this randomised controlled study was to investigate the effect of a 12-week high-intensity interval exercise training programme in DAL in addition to usual care in patients with COPD. |
| Databáze: | OpenAIRE |
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