Asymmetric Transfer Hydrogenation of CO and CN Bonds by Tethered RhIIICatalysts

Autor:	Daljit S. Matharu, Jose E. D. Martins, Martin Wills
Rok vydání:	2008
Předmět:	Ligand Aryl Organic Chemistry Enantioselective synthesis Noyori asymmetric hydrogenation General Chemistry Transfer hydrogenation Ring (chemistry) Biochemistry Medicinal chemistry Catalysis chemistry.chemical_compound chemistry Diamine Organic chemistry
Zdroj:	Chemistry - An Asian Journal. 3:1374-1383
ISSN:	1861-471X 1861-4728
DOI:	10.1002/asia.200800189
Popis:	Rh(III) catalysts containing a tetramethylcyclopentadienyl group linked by a 'tether' to a tosylated diamine ligand have previously been reported by our group for the asymmetric transfer hydrogenation (ATH) of ketones. The extension of these catalysts to the asymmetric reduction of imines, as well as to more highly functionalized substrates is reported. In some cases, the catalysts give better ee values than other methods for these transformations at lower catalyst loadings. The introduction of a methoxy group into the tethering aryl ring does not negate the performance of the catalyst, thus opening up a route to supported derivatives.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae89c39546c8feac4f7765651410de0 https://doi.org/10.1002/asia.200800189 Zobrazit plný text záznamu Plný text