N-Formylcarbamoylaspartame, a new aspartame-like sweetener. Synthesis and studies on stability and biological properties

Autor: Whj Boesten, van der Sj Wal, de Nk Koen Vries, Bhn Dassen, Emmo M. Meijer, Hans E. Schoemaker, van B Agen, Jcs Kleinjans
Přispěvatelé: Macromolecular and Organic Chemistry
Jazyk: angličtina
Rok vydání: 1991
Předmět:
Zdroj: Journal of Agricultural and Food Chemistry, 39(1), 154-158. American Chemical Society
ISSN: 0021-8561
Popis: A new aspartam-like sweetener (FC-APM) was prepared from aspartame (APM). Due to the protective group, FC-APM is less prone to diketopiperazine formation and therefore much more stable than aspartame at higher pH values and temperatures. A relatively stable metabolite of FC-APM was isolated from tissue extracts by preparative HPLC and identified by NMR.
Databáze: OpenAIRE