Effect of Dose on House Finch Infection with Western Equine Encephalomyelitis and St. Louis Encephalitis Viruses
| Autor: | Ying Fang, Robert E. Chiles, William K. Reisen, Vincent M. Martinez, Emily N. Green, Sharon L. Clark |
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| Rok vydání: | 2004 |
| Předmět: |
animal structures
viruses Encephalitis Virus St. Louis Viremia Biology Polymerase Chain Reaction Encephalitis Virus Western Equine Virus medicine Animals Vector (molecular biology) reproductive and urinary physiology DNA Primers Plaque-forming unit Base Sequence Encephalitis St. Louis General Veterinary St louis encephalitis virus diseases Encephalomyelitis Western Equine Viral Load medicine.disease Virology Chronic infection Infectious Diseases Insect Science behavior and behavior mechanisms Parasitology Finches Viral disease Encephalitis |
| Zdroj: | Journal of Medical Entomology. 41:978-981 |
| ISSN: | 1938-2928 0022-2585 |
| DOI: | 10.1603/0022-2585-41.5.978 |
| Popis: | House finches, Carpodacus mexicanus, were experimentally infected with high and standard doses of western equine encephalomyelitis virus (WEEV) or St. Louis encephalitis virus (SLEV) to determine whether high doses would produce an elevated viremia response and a high frequency of chronic infections. Finches inoculated with approximately100,000 plaque forming units (PFU) of WEEV or SLEV produced viremia and antibody responses similar to those in finches inoculated with approximately 100 PFU of WEEV or 1000 PFU of SLEV, the approximate quantities of virus expectorated by blood-feeding Culex tarsalis Coquillett. Infected finches were held through winter and then necropsied. Only one finch inoculated with the high dose of SLEV developed a chronic infection. Our data indicated that elevated infectious doses of virus may not increase the viremia level or the frequency of chronic infection in house finches. |
| Databáze: | OpenAIRE |
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