Linking KSHV to human cancer
| Autor: | Blossom Damania, Emily L. Wong |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Genes
Viral Lymphoma Biopsy viruses Viral Genes Genome Viral Disease Neoplasms hemic and lymphatic diseases medicine Animals Humans Sarcoma Kaposi Gene business.industry Castleman Disease virus diseases DNA virus biochemical phenomena metabolism and nutrition medicine.disease Virology Cell Transformation Neoplastic Oncology Herpesvirus 8 Human Cytokines Sarcoma Primary effusion lymphoma business Human herpesvirus Human cancer |
| Zdroj: | Current Oncology Reports. 7:349-356 |
| ISSN: | 1534-6269 1523-3790 |
| Popis: | Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8), has been linked to several malignancies in humans. KSHV is the etiologic agent associated with the development of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman's disease (MCD). KSHV is a double-stranded DNA virus that has been classified as a gammaherpesvirus. Here, we review the association of KSHV with human cancer, viral genes that may potentially be involved in the neoplastic process, and current therapies used to treat KS, PEL, and MCD. |
| Databáze: | OpenAIRE |
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