Cooling and Comfort: The COMFORTNeo-scale during therapeutic hypothermia after perinatal asphyxia
| Autor: | Inge A. Zonnenberg, Z. Hannink, Timo R. de Haan, Daphne H. M. Been-Emanuel, Koen P. Dijkman, A. H. van Kaam, Annemieke J. Brouwer, Peter H. Dijk, M. Jaspers, Y. Stuijk, A.F.J. van Heijst, Alexandra Zecic, Floris Groenendaal, Jeroen Dudink, S. Lagerweij, Filip Cools, Joke M. Wielenga, K. Ruhe, Monique Rijken, R. Dekker, H.L.M. van Straaten |
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| Přispěvatelé: | Pediatric surgery, VU University medical center, Amsterdam Reproduction & Development (AR&D), AGEM - Digestive immunity, Neonatology, AGEM - Endocrinology, metabolism and nutrition, Anesthesiology, Pediatrics, Radiology & Nuclear Medicine |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Mechanical ventilation
business.industry medicine.drug_class medicine.medical_treatment Analgesic Therapeutic effect Odds ratio Hypothermia medicine.disease Pediatrics Perinatal asphyxia 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Anesthesia Sedative Cohort Medicine medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Neonatal Nursing, 24(6), 313-317. Elsevier BV the PharmaCool studygroup 2018, ' Cooling and Comfort: The COMFORTNeo-scale during therapeutic hypothermia after perinatal asphyxia ', Journal of Neonatal Nursing, vol. 24, no. 6, pp. 313-317 . https://doi.org/10.1016/j.jnn.2018.07.004 Journal of Perinatal & Neonatal Nursing, 24, 313-317. Lippincott Williams & Wilkins |
| ISSN: | 1355-1841 0893-2190 |
| DOI: | 10.1016/j.jnn.2018.07.004 |
| Popis: | The therapeutic effect of moderate hypothermia in infants with HIE after perinatal asphyxia can be counteracted by stress which should therefore be minimized. Objective: of study was to gain insight in the COMFORTNeo-scale to measure stress during therapeutic hypothermia. Stress was measured prospectively by means of the COMFORTNeo-scale (CNS), twice a day, during hypothermia-, rewarming- and stabilization phase in a cohort of 133 neonates with perinatal asphyxia who participated in the PharmaCool study. A total of 994 CNS scores were collected; median score CNS 9 (IQR 7–11). Despite analgesic, sedative and anticonvulsant drugs 10% of the scores indicated moderate to severe stress during treatment. The use of these drugs as well as mechanical ventilation interfered with CNS score (respectively odds ratio 0.74 and 0.61) Interference of aEEG, hypothermia phase and gender were not confirmed. The COMFORTNeo-scale can, with the necessary caution, be used for the assessment of stress during therapeutic hypothermia treatment. Other options should be explored. |
| Databáze: | OpenAIRE |
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