EFFECT OF COMPLEX PLANT REMEDY ON THE MORPHOFUNCTIONAL STATE OF THE LIVER OF RATS WITH ETHANOL-INDUCED HEPATITIS
| Autor: | Viktoriya Ayusheeva, A.A. Toropova, Iraida Ubeeva, S. M. Nikolaev, Yanina Razuvaeva, Nadezhda Verlan |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2016 |
| Předmět: |
Hepatitis
medicine.medical_specialty achillea millefolium l Ethanol business.industry Science polygonum aviculare l cinnamomum cassia l Pharmacology medicine.disease Gastroenterology chemistry.chemical_compound complex plant remedy chemistry Internal medicine medicine ethanol-induced hepatitis zingiber officinalis l business urtica dioica l |
| Zdroj: | Acta Biomedica Scientifica, Vol 1, Iss 6, Pp 167-170 (2016) |
| ISSN: | 2587-9596 2541-9420 |
| Popis: | The influence of the complex plant remedy (Urtica dioica L., Polygonum aviculare L., Achillea millefolium L., Zingiber officinalis L., Cinnamomum cassia L.) on the morphofunctional state of the liver in rats with ethanol-induced hepatitis was studied. The liver injury was simulated with 40% ethanol introduction to rats in dose of 10.0 ml/kg for 7 days. The extract of the complex remedy was administered to animals in dose of 200 ml/kg for 14 days. The findings showed that the tested remedy inhibited the development of microcirculatory impairments, decreased the intensity of inflammatory infiltration and diminished the amount of hepatocytes subjected to adipose and cloudy degeneration as well as to necrotic changes. The increased amount of hypertrophied and binuclear hepatocytes in the area of the portal tract and central vein testifies reparation processes in the liver of the rats treated with the tested plant extract. |
| Databáze: | OpenAIRE |
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