Rubinstein-Taybi syndrome in children with tethered spinal cord
| Autor: | Benjamin C. Ling, Jack Rubinstein, Tomoko Tanaka, Kerry R. Crone |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Cauda Equina Urinary system medicine.medical_treatment Magnetic Resonance Imaging Cine medicine Humans Neural Tube Defects Urinary Bladder Neurogenic Child Gait Retrospective Studies Rubinstein-Taybi Syndrome Urinary bladder Lumbar Vertebrae medicine.diagnostic_test Rubinstein–Taybi syndrome business.industry Laminectomy Magnetic resonance imaging Retrospective cohort study General Medicine medicine.disease Spinal cord Magnetic Resonance Imaging Surgery medicine.anatomical_structure Treatment Outcome Urinary Incontinence Muscle Spasticity Child Preschool Female business Low Back Pain |
| Zdroj: | Journal of neurosurgery. 105 |
| ISSN: | 0022-3085 |
| Popis: | The authors identified eight patients with Rubinstein-Taybi syndrome (RTS) and examined how the underlying conditions of this syndrome can impede the detection of symptoms associated with a tethered spinal cord. They also reviewed the literature and did not find any published series describing such an association with this syndrome.In this retrospective review, the authors report the diagnosis, treatment, and outcome of tethered spinal cord in eight children (age range 2-14 years) with RTS. The patients presented between 1995 and 2003 with neurogenic bladder, decreased activity, gait disturbance, and low-back pain. The children were examined using whole-spine magnetic resonance (MR) imaging and, in recent years, their spinal cord movement was assessed using cine MR imaging. After undergoing lumbar laminectomy and spinal cord untethering procedures, six patients experienced improvement in symptoms associated with tethered spinal cord such as pain, urinary tract infection, incontinence, spasticity, and neurogenic bladder.Although some underlying conditions of RTS may mask the symptoms of a tethered spinal cord in children, careful attention to the patient's medical history as provided by his or her parents may aid in early diagnosis, evaluation, and treatment, thus preventing further neurological deterioration and leading to improved outcomes. |
| Databáze: | OpenAIRE |
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