Cervicomedullary primitive neuroectodermal tumor of the spine: Case report
| Autor: | Fred Bernardes Filho, Breno Nery, Eduardo Quaggio, Cecília Hissae Miyake, Isadora Salviano Teixeira Prado, Leandro César Tângari Pereira, Lígia Henriques Coronatto, Rodolfo Mendes Queiroz, Rodrigo Antônio Fernandes Costa, Lucas Giansante Abud |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Neuro-Oncology: Case Report medicine.medical_treatment Population neuroectodermal tumor law.invention Intramedullary rod law medicine Respiratory function education Neuroectodermal tumor education.field_of_study treatment business.industry primitive Microsurgery medicine.disease Cervicomedullary Junction Cervicomedullary Primitive neuroectodermal tumor Surgery pathology Neurology (clinical) Radiology business Febrile neutropenia intramedullary |
| Zdroj: | Surgical Neurology International |
| ISSN: | 2152-7806 2229-5097 |
| Popis: | Background: Intramedullary primitive neuroectodermal tumors (PNETs) are tumors found rarely in the cervical region, with only five such cases described in the literature. The available literature contains only one report regarding cervicomedullary junction PNET. Case Description: The authors present a case report of a 45-year-old male patient who had undergone urgent hospitalization owing to progressive tetraparesis and subtle impairment of respiratory function. He underwent magnetic resonance imaging, which showed an extensive enhancing cervical intramedullary tumor extending from C5 to the bulbar region. Since he developed severe impairment of respiratory function, he required tracheostomy. He then underwent microsurgery 2 days after his admission, and a partial tumor resection was performed. The pathological diagnosis of PNET of the cervicomedullary junction (CMJ) was made. He had slight worsening of strength after surgery with subsequent deterioration over the next 3 weeks. The tumor displayed aggressive growth; thus, radiotherapy was indicated. Unfortunately, he developed severe febrile neutropenia and died after 2 weeks of radiotherapy. Given the rarity of the condition, we wish to review the epidemiology, pathophysiology, and treatment options of his population. Conclusion: Intramedullary PNETs of the cervical spine and CMJ are exceedingly rare in adults; treatment of such patients remains a challenge, despite the modern neurosurgical armamentarium that is available. |
| Databáze: | OpenAIRE |
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