The Chemistry of Some Dalodesmidean Millipedes from Tasmania (Diplopoda, Polydesmida)
| Autor: | Donovan J. Robinson, Conor T. Hogan, William A. Shear, Ralph A. Saporito, Thomas F. Spande, Dylan M. Guthrie, Robert Mesibov, Tappey H. Jones |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Polydesmida
Fauna Pharmaceutical Science Zoology 010402 general chemistry 01 natural sciences Tasmania Analytical Chemistry Genus Drug Discovery Temperate climate Animals Arthropods Southern Hemisphere Pharmacology biology 010405 organic chemistry Chemistry Organic Chemistry Millipede Stereoisomerism Ketones biology.organism_classification 0104 chemical sciences Complementary and alternative medicine Chemical constituents Litter Molecular Medicine |
| Zdroj: | Journal of Natural Products. 81:171-177 |
| ISSN: | 1520-6025 0163-3864 |
| Popis: | Millipedes (Diplopoda) are well known for their toxic or repellent defensive secretions. As part of a larger investigation, we describe the chemical constituents of 14 species of Tasmanian millipedes in seven genera. Six species in the genus Gasterogramma were found to produce acyclic ketones, including the pungent unsaturated ketones 1, 2, and 6, and the novel (rel-3R,5S,7S)-3,5,7-trimethyl-2,8-decanedione (7b), for which the stereoconfiguration was established by stereoselective syntheses of pairs of isomers. These compounds have not been detected before in millipede defensive secretions. This report is the first on species of the suborder Dalodesmidea (Polydesmida), a dominant component of the soil and litter fauna of the temperate regions of the Southern Hemisphere. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|