Describing the resource utilisation and costs associated withvertebral fractures: the Build Better Bones with Exercise (B3E) Pilot Trial
| Autor: | Jenna C Gibbs, John D. Wark, S. Hassan, Soo Jin Seung, Maureen C. Ashe, Nicole Mittmann, Lora Giangregorio, R. E. Clark, Lehana Thabane, Alexandra Papaioannou, Caitlin McArthur, David L. Kendler, Jonathan D. Adachi, J. A. Templeton |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Endocrinology Diabetes and Metabolism Cost-Benefit Analysis Population Osteoporosis 030209 endocrinology & metabolism Pilot Projects 03 medical and health sciences 0302 clinical medicine Resource (project management) Quality of life Intervention (counseling) medicine Humans Adverse effect education health care economics and organizations Aged education.field_of_study business.industry Health Care Costs medicine.disease 3. Good health Exercise Therapy Cost driver Home exercise Physical therapy Quality of Life Spinal Fractures Female 030101 anatomy & morphology Quality-Adjusted Life Years business |
| Zdroj: | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 31(6) |
| ISSN: | 1433-2965 |
| Popis: | This analysis examined costs/resources of 141 women with vertebral fractures, randomised to a home exercise programme or control group. Total, mean costs and the incremental cost-effectiveness ratio (ICER) were calculated. Quality of life was collected. Cost drivers were caregiver time, medications and adverse events (AEs). Results show adding an exercise programme may reduce the risk of AEs. This exploratory economic analysis examined the health resource utilisation and costs experienced by women with vertebral fractures, and explored the effects of home exercise on those costs. Women ≥ 65 years with one or more X-ray-confirmed vertebral fractures were randomised 1:1 to a 12-month home exercise programme or equal attention control group. Clinical and health system resources were collected during monthly phone calls and daily diaries completed by participants. Intervention costs were included. Unit costs were applied to health system resources. Quality of life (QoL) information was collected via EQ-5D-5L at baseline, 6 and 12 months. One hundred and forty-one women were randomised. Overall total costs (CAD 2018) were $664,923 (intervention) and $614,033 (control), respectively. The top three cost drivers were caregiver time ($250,269 and $240,811), medications ($151,000 and $122,145) and AEs ($58,807 and $71,981). The mean cost per intervention participant of $9365 ± $9988 was higher compared with the mean cost per control participant of $8772 ± $9718. The mean EQ-5D index score was higher for the intervention participants (0.81 ± 0.11) compared with that of controls (0.79 ± 0.13). The differences in quality-adjusted life year (QALY) (0.02) and mean cost ($593) were used to calculate the ICER of $29,650. Women with osteoporosis with a previous fracture experience a number of resources and associated costs that impact their care and quality of life. Caregiver time, medications and AEs are the biggest cost drivers for this population. The next steps would be to expand this feasibility study with more participants, longer-term follow-up and more regional variability. |
| Databáze: | OpenAIRE |
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