Prospective study comparing skin impedance with EEG parameters during the induction of anaesthesia with fentanyl and etomidate
| Autor: | Enrico Monaca, Tobias Jüttner, M Gerhard, Oliver Danzeisen, Niels Rahe-Meyer, Michael Winterhalter, S Münte, Ludwig Hoy, Peter Kienbaum |
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| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.medical_specialty etomidate lcsh:Medicine Blood Pressure Electroencephalography fentanyl Fentanyl Coronary artery bypass surgery Heart Rate Etomidate Skin Physiological Phenomena Heart rate medicine Humans general anaesthesia General anaesthesia Prospective Studies skin impedance Skin medicine.diagnostic_test business.industry Research lcsh:R General Medicine Middle Aged Anesthetics Combined Electric Stimulation Cardiac surgery Electrophysiology Anesthesia Anesthesia Intravenous Female business Anesthetics Intravenous cardiac surgery medicine.drug |
| Zdroj: | European Journal of Medical Research, Vol 15, Iss 2, p 47 (2010) European Journal of Medical Research Europe PubMed Central |
| ISSN: | 2047-783X |
| DOI: | 10.1186/2047-783x-15-2-47 |
| Popis: | Objective Sympathetic stimulation leads to a change in electrical skin impedance. So far it is unclear whether this effect can be used to measure the effects of anaesthetics during general anaesthesia. The aim of this prospective study is to determine the electrical skin impedance during induction of anaesthesia for coronary artery bypass surgery with fentanyl and etomidate. Methods The electrical skin impedance was measured with the help of an electro-sympathicograph (ESG). In 47 patients scheduled for elective cardiac surgery, anaesthesia was induced with intravenous fentanyl 10 μg/kg and etomidate 0.3 mg/kg. During induction, the ESG (Electrosympathicograph), BIS (Bispectral IndeX), BP (arterial blood pressure) and HR (heart rate) values of each patient were recorded every 20 seconds. The observation period from administration of fentanyl to intubation for surgery lasted 4 min. Results The ESG recorded significant changes in the electrical skin impedance after administration of fentanyl and etomidate(p < 0.05). During induction of anaesthesia, significant changes of BIS, HR and blood pressure were observed as well (p < 0.05). Conclusions The electrical skin impedance measurement may be used to monitor the effects of anesthetics during general anaesthesia. |
| Databáze: | OpenAIRE |
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