An Automated Synthesis–Purification–Sample-Management Platform for the Accelerated Generation of Pharmaceutical Candidates

Autor: Noah P. Tu, Stevan W. Djuric, Philip A. Searle, Jeffrey Y. Pan, J. David Sutherland, Thomas A. Nemcek, Jill E. Hochlowski
Rok vydání: 2014
Předmět:
Zdroj: SLAS Technology. 19:176-182
ISSN: 2472-6303
Popis: A flexible and integrated flow-chemistry-synthesis-purification compound-generation and sample-management platform has been developed to accelerate the production of small-molecule organic-compound drug candidates in pharmaceutical research. Central to the integrated system is a Mitsubishi robot, which hands off samples throughout the process to the next station, including synthesis and purification, sample dispensing for purity and quantification analysis, dry-down, and aliquot generation.
Databáze: OpenAIRE