Effect of Percutaneous Edge-to-Edge Repair on Mitral Valve Area and Its Association With Pulmonary Hypertension and Outcomes
| Autor: | Takahiro Shiota, Yuji Itabashi, Saibal Kar, Hiroto Utsunomiya, Moody Makar, Sayuki Kobayashi, Asma Hussaini, Alfredo Trento, Florian Rader, Robert J. Siegel |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Cardiac Catheterization medicine.medical_specialty Time Factors Percutaneous Hypertension Pulmonary Echocardiography Three-Dimensional 030204 cardiovascular system & hematology complex mixtures 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Pulmonary Wedge Pressure 030212 general & internal medicine Pulmonary wedge pressure Aged Retrospective Studies Heart Valve Prosthesis Implantation Mitral regurgitation business.industry MitraClip Mitral Valve Insufficiency Retrospective cohort study Prognosis medicine.disease Pulmonary hypertension Surgery Treatment Outcome Heart failure Cardiology Mitral Valve Female Cardiology and Cardiovascular Medicine business Echocardiography Transesophageal Percutaneous Mitral Valve Repair Follow-Up Studies |
| Zdroj: | The American Journal of Cardiology. 120:662-669 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/j.amjcard.2017.05.036 |
| Popis: | Percutaneous edge-to-edge repair using the MitraClip system causes reduction in mitral valve area (MVA). However, its clinical impact is not fully elucidated. This study assessed the impact of postprocedural MVA reduction on pulmonary hypertension and outcomes. A total of 92 patients with grades 3 to 4 + mitral regurgitation (MR) who underwent MitraClip therapy were retrospectively reviewed. Using intraprocedural, 3-dimensional transesophageal echocardiography, postprocedural MVA was obtained by 2 optimized planes through the medial and lateral orifices of the repaired valve. MVA was reduced by 60.1% immediately after MitraClip procedure (p0.001). Postprocedural MVA correlated moderately with mean transmitral pressure gradient (TMPG) in the majority of patients (r = -0.56, p0.001), but discordance of MVA and TMPG was observed in 40% of patients. In multivariable linear regression analysis, postprocedural MVA ≤1.94 cm |
| Databáze: | OpenAIRE |
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