Successful pregnancy following novel IVF protocol and transmyometrial embryo transfer after radical vaginal trachelectomy
| Autor: | Bernard Couturier, Isaac Jacques Kadoch, Louise Lapensée, Robert Hemmings, François Bissonnette, Wael Jamal, Simon Phillips |
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| Rok vydání: | 2009 |
| Předmět: |
Infertility
Adult medicine.medical_specialty medicine.medical_treatment Reproductive medicine Uterine Cervical Neoplasms Cervix Uteri Fertilization in Vitro Adenocarcinoma Gynecologic Surgical Procedures Pregnancy medicine Humans Caesarean section Ultrasonography Cervical cancer Gynecology Obstetrics business.industry Pregnancy Outcome Obstetrics and Gynecology Gestational age medicine.disease Embryo Transfer Embryo transfer Reproductive Medicine Female Live birth business Developmental Biology |
| Zdroj: | Reproductive biomedicine online. 18(5) |
| ISSN: | 1472-6491 |
| Popis: | Radical vaginal trachelectomy in patients with early-stage cervical cancer is an oncologically safe procedure in well-selected patients. Successful pregnancy in a patient with radical vaginal trachelectomy is possible, with two-thirds of pregnancies resulting in live birth. However, it presents a great challenge for assisted reproductive techniques and reproductive medicine in cases with subsequent severe cervical stenosis. This is a report of a 38-year-old patient who underwent radical vaginal trachelectomy at the age of 33 years for early stage (IA2) adenocarcinoma and subsequently presented with infertility due to cervical factors. The patient underwent ovarian stimulation using a novel SMART (Stimulation with Minimal Adverse effects, Retrieval and Transfer)-IVF protocol. As it was impossible to perform transcervical embryo transfer with an almost absent severely stenotic cervical opening, a transmyometrial embryo transfer under ultrasound guidance was performed. This resulted in a successful singleton full-term pregnancy delivered by Caesarean section at gestational age 37 weeks. As far as is known, this is the first reported case of successful pregnancy conceived by IVF with transmyometrial embryo transfer for a patient who had previously undergone radical vaginal trachelectomy. |
| Databáze: | OpenAIRE |
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