pIChemiSt ─ Free Tool for the Calculation of Isoelectric Points of Modified Peptides

Autor: Andrey I. Frolov, Sunay V. Chankeshwara, Zeyed Abdulkarim, Gian Marco Ghiandoni
Rok vydání: 2022
Předmět:
Zdroj: Journal of Chemical Information and Modeling. 63:187-196
ISSN: 1549-960X
1549-9596
DOI: 10.1021/acs.jcim.2c01261
Popis: The isoelectric point (pI) is a fundamental physicochemical property of peptides and proteins. It is widely used to steer design away from low solubility and aggregation and guide peptide separation and purification. Experimental measurements of pI can be replaced by calculations knowing the ionizable groups of peptides and their corresponding p
Databáze: OpenAIRE