Omega-3 fatty acids as feed supplement modulates blood formation and body weight in Rattus norvegicus model
| Autor: | Emmanuel Ikechukwu Nnamonu, Bernard Obialo Mgbenka, Godwin C. Ugwu, Edmund C. Mbegbu, Bede Izuchukwu Ezewudo, Chiemekam Samuel Ezechukwu |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Adult male 030309 nutrition & dietetics 030209 endocrinology & metabolism Biology Body weight 03 medical and health sciences 0302 clinical medicine Animal science Internal medicine lcsh:Zoology Male rats Omega-3 fatty acids medicine lcsh:QL1-991 Feed supplement 0303 health sciences Hematology Metabolism Blood erythrocytes Rats Mean cell haemoglobin concentration Haematological parameters medicine.symptom Weight gain |
| Zdroj: | Journal of Basic and Applied Zoology, Vol 81, Iss 1, Pp 1-8 (2020) |
| ISSN: | 2090-990X |
| DOI: | 10.1186/s41936-020-00155-1 |
| Popis: | Background Omega-3 fatty acids’ inclusion as feed supplement in the diets of both human and animals has been found to play a significant role in body metabolism. The aim of this present study was to evaluate the effects of graded doses of omega-3 fatty acids on haematology and body weight of adult male and female Rattus norvegicus (Wistar albino rats) as a model animal. Methods A total of seventy-two adult male and female albino rats were randomly assigned into two experimental units. Each unit was grouped into three and received different treatment diets. Blood erythrocytes and weight were sampled on days 0, 14 and 28 to evaluate haematological parameters and body weight. Results Results showed concentration- and time-dependent significant increases (p < 0.05) in the packed cell volume (PCV), haemoglobin (Hb), white blood cells (WBCs), mean cell volume (MCV) and mean cell haemoglobin (MCH) and non-significant change (p > 0.05) in the red blood cells (RBCs) and mean cell haemoglobin concentration (MCHC) in male rats after day 0. In female rats, significant increases (p < 0.05) were recorded in the PCV, Hb, MCV and MCH, whereas no significant increase was observed in the RBCs. Activities of WBCs and MCHC showed mixed trend in female rats. The results of the body weight recorded non-significant increases (p > 0.05) in both experimental units. Conclusion Our findings depict that the use of omega-3 fatty acids in the diets of both male and female rats produced a dose-dependent effect on blood formation while its role in controlling weight gain was observed. Hence, its intake in both animal and human diets should be rightly prescribed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink