Impact of type 1 diabetes mellitus and celiac disease on nutrition and quality of life
| Autor: | Maria Lúcia Corrêa-Giannella, Marcia Nery, J G Nunes-Silva, Valéria S. Nunes, D Evazian, S Mlss Trecco, R P Schwartz, Márcia Silva Queiroz |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Blood Glucose Male medicine.medical_specialty Endocrinology Diabetes and Metabolism Population Nutritional Status 030209 endocrinology & metabolism QUALIDADE DE VIDA Personal Satisfaction Gastroenterology Body Mass Index Diet Gluten-Free Young Adult 03 medical and health sciences 0302 clinical medicine Internal medicine Diabetes mellitus Internal Medicine medicine Humans 030212 general & internal medicine education Glycemic education.field_of_study Type 1 diabetes business.industry nutritional and metabolic diseases Middle Aged medicine.disease Obesity Celiac Disease Diabetes Mellitus Type 1 Mental Health Endocrinology Quality of Life Patient Compliance Female Original Article Gluten free Metabolic syndrome business Body mass index |
| Zdroj: | Nutrition & Diabetes Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| ISSN: | 2044-4052 |
| DOI: | 10.1038/nutd.2016.43 |
| Popis: | Objective: Type 1 diabetes mellitus (T1DM) and celiac disease (CD) are autoimmune diseases and have similar genetic patterns. T1DM treatment is based on diet, physical activity and insulin therapy, whereas CD depends on dietary changes with restriction of wheat, rye and barley. The aim of the study was to evaluate the quality of life (QoL) of individuals with the association of T1DM and CD, to characterize their nutritional status and to compare it with those with only one disease and healthier controls. Subjects/Methods: Sixty patients controlled by sex, age and body mass index (BMI) were stratified by previous diagnosis in: T1DM and CD (DMCD group); T1DM (DM group); CD (CD group); or healthy participants (HC). The SF-36 questionnaire was applied to assess psychological well being and results were compared with glycemic control and presence of complications related to diabetes, adhesion to gluten-free diet (GFD). Nutritional status and body mass composition were determined by BMI, waist circumference, bioimpedance, general laboratory tests and whole-body densitometry. Results: The time of diagnosis of T1DM was similar between DMCD and DM groups; however, the duration of CD was significantly higher in the CD group compared with DMCD. The SF-36 analysis revealed statistically significant differences between DM and HC groups in two domains: general health (P=0.042) and energy/vitality (P=0.012). QoL was also correlated with compliance to a GFD, and scores were similar in both groups: DMCD and CD. Forty percent of individuals in the CD group had visceral fat area above 100 cm2, as opposed to 20% in the other groups. Conclusions: Individuals of DMCD group had similar scores to DM, CD and HC on QoL, as well as on their nutritional status and bone metabolism. Thereby, we should conclude that the association of T1DM and CD did not deteriorate their health status. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|