Psoriasis-associated impairment of CCL27/CCR10-derived regulation leads to IL-17A/IL-22-producing skin T-cell overactivation
Autor: | Yong Wang, Na Xiong, Chao Li, Ming Xu, Micha L. Davila, James Coyne, Wei Bei Wang |
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Rok vydání: | 2019 |
Předmět: |
0301 basic medicine
Chemokine T cell T-Lymphocytes Immunology Inflammation Receptors CCR10 Lymphocyte Activation Article Interleukin 22 03 medical and health sciences Mice 0302 clinical medicine Psoriasis medicine Immunology and Allergy Animals CCR10 Receptor Skin biology integumentary system business.industry Chemokine CCL27 Interleukins Interleukin-17 medicine.disease 030104 developmental biology medicine.anatomical_structure biology.protein CCL27 medicine.symptom business 030215 immunology |
Zdroj: | J Allergy Clin Immunol |
ISSN: | 1097-6825 |
Popis: | Psoriasis-associated suppression of the skin-specific chemokine/receptor CCL27/CCR10 axis leads to enhanced pathogenic IL-17A/IL-22-producing skin T cell activation and inflammation. |
Databáze: | OpenAIRE |
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