Variability of Predialytic, Intradialytic, and Postdialytic Blood Pressures in the Course of a Week
Autor: | Judith J. Dasselaar, Paul E. de Jong, Len A. Usvyat, Jurjen K. Oosterhuis, Casper F. M. Franssen, Ralf Westerhuis, Peter Kotanko, Johanna Kuipers, Yuedong Wang, Jeffrey J. Sands |
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Jazyk: | angličtina |
Rok vydání: | 2013 |
Předmět: |
Male
Systematic difference medicine.medical_specialty hypotension Time Factors medicine.medical_treatment Ultrafiltration Hemodynamics VOLUME CHANGES Renal Dialysis Humans Medicine Prospective Studies Dialysis Netherlands DIALYSIS SCHEDULE hemodialysis business.industry MORTALITY Maintenance hemodialysis Middle Aged United States Surgery Blood pressure Nephrology Anesthesia ultrafiltration Female Hemodialysis medicine.symptom business Weight gain |
Zdroj: | American Journal of Kidney Diseases, 62(4), 779-788. W B SAUNDERS CO-ELSEVIER INC |
ISSN: | 1523-6838 0272-6386 |
DOI: | 10.1053/j.ajkd.2013.03.034 |
Popis: | Background: Patients with thrice-weekly hemodialysis have higher predialysis weights and ultrafiltration rates at the first compared with subsequent dialysis sessions of the week. We hypothesized that these variations in weight and ultrafiltration rate are associated with a systematic difference in blood pressure.Study Design: Observational study.Setting & Participants: During 3 months, we prospectively collected hemodynamic data for 4,007 hemodialysis sessions involving 124 Dutch patients. A similar analysis was performed with 789 US patients, comprising 6,060 hemodialysis sessions.Factor: First versus subsequent hemodialysis sessions of the week.Outcomes: Blood pressure.Measurements: Blood pressure, weight, and ultrafiltration rate were analyzed separately for the first, second, and third dialysis sessions of the week. Comparisons were made with linear mixed models.Results: In Dutch patients, predialysis weight and ultrafiltration rate were significantly greater at the first compared with subsequent hemodialysis sessions of the week (P Limitations: Dry weight was not assessed by objective methods.Conclusions: Blood pressure of patients on a thrice-weekly dialysis schedule varies systematically over the week. Predialysis blood pressure is highest at the first hemodialysis session of the week, most likely due to greater interdialytic weight gain. Intra-and postdialytic blood pressures also are highest at the first session of the week despite higher ultrafiltration rates. (C) 2013 by the National Kidney Foundation, Inc. |
Databáze: | OpenAIRE |
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