Variability of Predialytic, Intradialytic, and Postdialytic Blood Pressures in the Course of a Week

Autor: Judith J. Dasselaar, Paul E. de Jong, Len A. Usvyat, Jurjen K. Oosterhuis, Casper F. M. Franssen, Ralf Westerhuis, Peter Kotanko, Johanna Kuipers, Yuedong Wang, Jeffrey J. Sands
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: American Journal of Kidney Diseases, 62(4), 779-788. W B SAUNDERS CO-ELSEVIER INC
ISSN: 1523-6838
0272-6386
DOI: 10.1053/j.ajkd.2013.03.034
Popis: Background: Patients with thrice-weekly hemodialysis have higher predialysis weights and ultrafiltration rates at the first compared with subsequent dialysis sessions of the week. We hypothesized that these variations in weight and ultrafiltration rate are associated with a systematic difference in blood pressure.Study Design: Observational study.Setting & Participants: During 3 months, we prospectively collected hemodynamic data for 4,007 hemodialysis sessions involving 124 Dutch patients. A similar analysis was performed with 789 US patients, comprising 6,060 hemodialysis sessions.Factor: First versus subsequent hemodialysis sessions of the week.Outcomes: Blood pressure.Measurements: Blood pressure, weight, and ultrafiltration rate were analyzed separately for the first, second, and third dialysis sessions of the week. Comparisons were made with linear mixed models.Results: In Dutch patients, predialysis weight and ultrafiltration rate were significantly greater at the first compared with subsequent hemodialysis sessions of the week (P Limitations: Dry weight was not assessed by objective methods.Conclusions: Blood pressure of patients on a thrice-weekly dialysis schedule varies systematically over the week. Predialysis blood pressure is highest at the first hemodialysis session of the week, most likely due to greater interdialytic weight gain. Intra-and postdialytic blood pressures also are highest at the first session of the week despite higher ultrafiltration rates. (C) 2013 by the National Kidney Foundation, Inc.
Databáze: OpenAIRE