Selectively deoxygenated sulfated tetrasaccharides as probes for the investigation of smooth muscle cell antiproliferative activity

Autor:	Niggi Iberg, Michel Trumtel, Hans Peter Wessel, Marie-Claude Viaud
Rok vydání:	1996
Předmět:	Chemistry Stereochemistry Organic Chemistry Clinical Biochemistry Cell Pharmaceutical Science Biological activity Biochemistry medicine.anatomical_structure Sulfation Smooth muscle Drug Discovery medicine Molecular Medicine Molecule Molecular Biology
Zdroj:	ResearcherID
ISSN:	0960-894X
DOI:	10.1016/0960-894x(95)00554-7
Popis:	Selectively deoxygenated analogues of highly (ca. 80 %) sulfated β-maltosyl-(1→4)-α,α-trehalose were investigated to map the importance of the individual sulfates for biological activity. Single deoxygenations led to activity losses up to 30 %; the essential sulfates are located on the outer glucopyranosyl rings of the molecule.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8c6d009b127cb99da371ac1ed3a8ea https://doi.org/10.1016/0960-894x(95)00554-7 Zobrazit plný text záznamu Full Text from ScienceDirect