Feminizing adrenal tumors: Our experience about three cases
Autor: | Smina Yahiaoui, Said Azzoug, Nora Soumeya Fedala, Sabrina Souidi, Farida Chentli, Ilyes Bekkaye |
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Jazyk: | angličtina |
Rok vydání: | 2013 |
Předmět: |
Pediatrics
medicine.medical_specialty gynecomastia Endocrinology Diabetes and Metabolism Case Report with Review of Literature Adrenal neoplasm Malignancy lcsh:Diseases of the endocrine glands. Clinical endocrinology Metastasis Endocrinology medicine hypogonadism lcsh:RC799-869 Adrenal Pathological Adrenal tumors High estradiol Gynecology lcsh:RC648-665 business.industry medicine.disease Decreased Libido feminizing tumors Gynecomastia lcsh:Diseases of the digestive system. Gastroenterology business |
Zdroj: | Indian Journal of Endocrinology and Metabolism Indian Journal of Endocrinology and Metabolism, Vol 17, Iss 3, Pp 509-513 (2013) |
ISSN: | 2230-9500 2230-8210 |
Popis: | Feminizing adrenal tumors (FATs) are very rare as they account for less than 2% of all the adrenal neoplasms. Their prognosis is deemed to be very poor. We aimed to present a mono centre (adult and pediatric) experience over a long period of time (January 1980 to Jun 2012). During the study period, we observed only three cases in men aged 22 (2 cases) and 45 (1 case). They all consulted for a painful gynecomastia, decreased libido and impotency. Estradiol was high in two cases at presentation, and after a relapsing tumor in the third one. All had big adrenal tumors (5.9, 6, and 17 cm), and a mixed secretion composed by high estradiol and cortisol. The pathological study argued for malignancy in two cases. But, only one had diffuse metastasis and died 4 years after diagnosis; the others diagnosed one and three years ago are still alive without any metastasis or relapsing. |
Databáze: | OpenAIRE |
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