Multi-route antifungal administration in the management of urinary Candida glabrata bezoar
| Autor: | Dickon Hayne, Jeanie Misko, John Dyer, Pravin Viswambaram, Matthew Rawlins, Sarah Clark |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Urology Urinary system 030232 urology & nephrology Hydronephrosis lcsh:RC870-923 Flucytosine 03 medical and health sciences 0302 clinical medicine Amphotericin B Medicine Percutaneous nephrostomy tube Candida glabrata biology business.industry Inflammation and Infection lcsh:Diseases of the genitourinary system. Urology medicine.disease biology.organism_classification medicine.anatomical_structure Urinary fungal bezoar 030220 oncology & carcinogenesis Bezoar business Renal pelvis Fluconazole medicine.drug |
| Zdroj: | Urology Case Reports Urology Case Reports, Vol 33, Iss, Pp 101275-(2020) |
| ISSN: | 2214-4420 |
| DOI: | 10.1016/j.eucr.2020.101275 |
| Popis: | A 65-year-old lady was admitted with urosepsis and imaging suggesting right sided hydronephrosis secondary to a filling defect consistent with a fungal bezoar. An indwelling urinary catheter and a right percutaneous nephrostomy tube were inserted. Candida glabrata cultured from urine was resistant to fluconazole. Amphotericin B was instilled into the renal pelvis via the nephrostomy tube while intravenous liposomal amphotericin was administered daily along with oral flucytosine. This multi-modal antifungal administration was continued for 14 days. Clinical and biochemical improvement was achieved and repeat imaging showed complete resolution of the filling defects and hydronephrosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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