Involvement of L-carnitine in cellular metabolism: Beyond Acyl-CoA transport
Autor: | Sebastián Pablo Chapela, Norberto Kriguer, Ezequiel Hernán Fernández, Carlos A. Stella |
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Jazyk: | angličtina |
Rok vydání: | 2009 |
Předmět: |
CIENCIAS MÉDICAS Y DE LA SALUD
Organic Cation Transport Proteins ACETYLATION Apoptosis Biology Acyl-CoA chemistry.chemical_compound Pharmacokinetics Carnitine Drug Discovery medicine Acetyl-L-carnitine ACETYL-L-CARNITINE Animals Humans Solute Carrier Family 22 Member 5 FREE RADICALS Pharmacology Cellular metabolism Acetylation Biological Transport General Medicine Bioquímica y Biología Molecular Carnitine metabolism APOPTOSIS Medicina Básica chemistry Biochemistry Mitochondrial matrix Acyl Coenzyme A medicine.drug CARNITINE |
Popis: | Carnitine is well-known for its role in the transport of fatty acids to the mitochondrial matrix, where β-oxidation takes place. This work describes novel functions for this compound and novel data on its pharmacokinetics. Fil: Chapela, Sebastián Pablo. Universidad de Buenos Aires; Argentina Fil: Kriguer, N.. Universidad de Buenos Aires; Argentina Fil: Fernández, Ezequiel Hernán. Universidad de Buenos Aires; Argentina Fil: Stella, Carlos Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; Argentina |
Databáze: | OpenAIRE |
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