Morphologic changes following intraarticular inoculation of Mycoplasma bovis in calves
| Autor: | M. E. Tourtellotte, M. J. Ryan, Tsu-Ju (Thomas) Yang, D. L. Hill, D. S. Wyand |
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| Rok vydání: | 1983 |
| Předmět: |
musculoskeletal diseases
0301 basic medicine Male Pathology medicine.medical_specialty 040301 veterinary sciences Pannus Arthritis Cattle Diseases 0403 veterinary science 03 medical and health sciences Platelet Adhesiveness Synovitis medicine Animals Mycoplasma Infections Arthritis Infectious Tenosynovitis General Veterinary business.industry Cartilage Goats Granulation tissue Thrombosis 04 agricultural and veterinary sciences medicine.disease Neutrophilia 030104 developmental biology medicine.anatomical_structure Lameness Immunology Cattle Joints medicine.symptom business |
| Zdroj: | Veterinary pathology. 20(4) |
| ISSN: | 0300-9858 |
| Popis: | Intraarticular inoculation of Mycoplasma bovis into the joints of six-week-old calves caused severe arthritis in five inoculates and mild arthritis in a sixth. Intraarticular inoculation of killed M. bovis did not cause arthritis.Arthritic calves had fever, joint swelling, lameness, neutrophilia, and intercurrent pneumonia from which M. bovis could not be recovered.Gross lesions were massive fibrinosuppurative synovitis and tenosynovitis, erosion of cartilage, and its replacement by polypoid granulation tissue. Histologic lesions were extensive ulceration of synovial membranes, leukocytic infiltration of the suhsynovium, congestion, hyperemia, and thrombosis of the subsynovial vessels. Cartilage erosion was accompanied by chronic osteomyelitis and formation of pannus tissue.The presence of thrombi and platelet aggregates suggests that the inflammatory process in the synovium may arise from the interaction of M. bovis with the vasculature and the coagulation process of the host. |
| Databáze: | OpenAIRE |
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