Long-term prognosis after acute kidney injury requiring renal replacement therapy
| Autor: | Jérôme Pugin, Thomas V. Perneger, Pierre-Yves Martin, Patrick Saudan, Jacques-André Romand, Pierre-Alain Triverio |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Nephrology
Male medicine.medical_specialty Time Factors medicine.medical_treatment Urology Renal function urologic and male genital diseases Internal medicine Hemofiltration medicine Humans Renal replacement therapy Dialysis ddc:613 Aged ddc:616 Transplantation ddc:617 business.industry Acute kidney injury Acute Kidney Injury Middle Aged medicine.disease Prognosis female genital diseases and pregnancy complications Surgery Renal Replacement Therapy Survival Rate Acute Kidney Injury/*mortality/*therapy Female Hemodialysis business Kidney disease |
| Zdroj: | Nephrology, Dialysis, Transplantation, Vol. 24, No 7 (2009) pp. 2186-2189 |
| ISSN: | 0931-0509 |
| Popis: | BACKGROUND: Data on the long-term survival and renal function of patients with acute kidney injury (AKI) treated with continuous renal replacement therapy are scarce. METHODS: We investigated the 3-year survival and need for chronic dialysis in critically ill patients, who had survived an episode of AKI requiring continuous renal replacement therapy. RESULTS: A total of 206 ICU patients with AKI were randomized in a trial comparing haemofiltration versus haemodiafiltration. Of these, 95 (46%) survived at 90 days. Post-discharge information relating to 3-year survival and renal function was successfully obtained in 89 (94%) of the patients. Of the 89 patients studied, chronic kidney disease (CKD) was present in 32 subjects from the onset, and CKD developed de novo in 25 patients following AKI. End-stage renal disease (ESRD) developed in 9 patients (of whom 8 had pre-existing CKD) and 29 patients died. Three-year survival was 67% overall; the mortality at 3 years was 50% for those with pre-existing kidney disease, and 71 and 82% for those with de novo and without CKD, respectively. CONCLUSION: After an episode of AKI necessitating a continuous renal replacement therapy, rapid progression to ESKD is commonly observed in patients with pre-existing chronic renal impairment. Medical care with an emphasis on nephroprotection is necessary in these patients. |
| Databáze: | OpenAIRE |
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