TASTE MASKING IN SYRUP CONTAINING HERBAL BITTER DRUGS: FORMULATION, STANDARDIZATION AND STABILITY STUDIES

Autor: B. E. Wanjari, M. V. Nema, A. S. Dongarwar ., T. P. Nimbekar
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: International Journal of Biomedical and Advance Research; Vol. 2 No. 3 (2011): Mar; 103-116
ISSN: 2229-3809
2455-0558
DOI: 10.7439/ijbar.v2i3
Popis: Taste masking of bitter drugs has been challenge to scientists as taste is an important parameter governing patient compliance. Several oral pharmaceuticals, numerous food and beverage products and bulking agents have unpleasant bitter taste. In order to ensure patient compliance bitterness masking becomes essential. The desire of improving the palatability has prompted the development of numerous formulations with improved performance and acceptability. Several approaches namely sensory, barrier, chemical and complexation have been tried to mask the unpleasant taste of formulation. The purpose of the present was to evaluate the bitterness of the prepared syrup formulation by using human taste sensor.
Databáze: OpenAIRE