Chitosan/copper nanocomposites: Correlation between electrical and antibacterial properties
| Autor: | Evgen Prokhorov, Eduardo A. Elizalde-Peña, Yuriy Kovalenko, Beatriz Liliana España-Sánchez, Milton Vázquez-Lepe, Felipe Padilla-Vaca, Gabriel Luna-Bárcenas, Martha Cruz-Soto |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Staphylococcus aureus
Materials science chemistry.chemical_element Microbial Sensitivity Tests 02 engineering and technology 01 natural sciences Nanocomposites Chitosan Metal chemistry.chemical_compound Colloid and Surface Chemistry Electricity X-Ray Diffraction X-ray photoelectron spectroscopy Spectroscopy Fourier Transform Infrared 0103 physical sciences Escherichia coli Physical and Theoretical Chemistry Fourier transform infrared spectroscopy Nanocomposite 010304 chemical physics Photoelectron Spectroscopy Electric Conductivity Percolation threshold Surfaces and Interfaces General Medicine 021001 nanoscience & nanotechnology Copper Anti-Bacterial Agents chemistry visual_art visual_art.visual_art_medium 0210 nano-technology Antibacterial activity Biotechnology Nuclear chemistry |
| Zdroj: | Colloids and Surfaces B: Biointerfaces. 180:186-192 |
| ISSN: | 0927-7765 |
| Popis: | Correlation between electrical and antibacterial properties of chitosan/copper nanocomposites (CS/CuNPs) is investigated. We aim at achieving the minimum CuNPs concentration in a CS-matrix while keeping high antibacterial activity. UV–vis, TEM and XRD measurements confirms the formation of polygonal metallic CuNPs (ca. 30–50 nm). Interactions between NH2/OH groups of CS and CuNPs were determined by FTIR and XPS suggesting Cu chelation-induced mechanism during the CuNPs formation. DC electrical conductivity measurements reveals a percolation threshold at CuNPs volumetric concentration of ca. 0.143%. Antibacterial assays against Gram-positive bacteria and DC measurements helps correlate the antibacterial potency to the electron transfer between the negatively charged bacteria and CuNPs. Our study suggests that nanocomposite’s maximum antibacterial activity is obtained below the electrical percolation threshold at extremely low CuNPs concentrations; this fact may prove useful in the design of nontoxic nanocomposites for biomedical applications. |
| Databáze: | OpenAIRE |
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