Risk factors of erectile dysfunction among diabetes patients in Africa: A systematic review and meta-analysis
| Autor: | Yared Asmare Aynalem, Tadesse Yirga Akalu, Wondimeneh Shibabaw Shiferaw, Habtamu Abera Areri, Pammla Petrucka |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Endocrinology Diabetes and Metabolism Sexual dysfunction 030209 endocrinology & metabolism Disease Review lcsh:Diseases of the endocrine glands. Clinical endocrinology 03 medical and health sciences 0302 clinical medicine Endocrinology Diabetes mellitus Internal medicine DM diabetes mellitus Medicine Erectile dysfunction 030212 general & internal medicine ED erectile dysfunction lcsh:RC648-665 business.industry Publication bias Odds ratio medicine.disease AOR adjusted odds ratio CI confidence interval Peripheral neuropathy Meta-analysis Africa medicine.symptom business PRISMA Preferred Reporting Items for Systematic Reviews and Meta-Analyses Impotence |
| Zdroj: | Journal of Clinical & Translational Endocrinology Journal of Clinical & Translational Endocrinology, Vol 21, Iss, Pp 100232-(2020) |
| ISSN: | 2214-6237 |
| Popis: | Background: Erectile dysfunction in men is a common underestimated complication of diabetes mellitus, which is becoming a significant public health problem both in developing and developed countries. Erectile dysfunction threatens the well-being of clients, hence determining its risk factors and controlling it at an early stage is vital to preventing serious consequences and the burden of the disease. Therefore, this study aimed to systematically evaluate erectile dysfunction risk factors in patients with diabetes mellitus in Africa. Methods: PubMed, Web of Science, Scopus, African Journals Online, Wiley Online Library and Google Scholar were searched and complemented by manual searches. Egger's regression test was used to determine publication bias. The I2 statistic was used to check heterogeneity between the studies. DerSimonian and Laird random-effects model was applied to estimate pooled effect size, odds ratios, and 95% confidence interval across studies. STATA version 14 statistical software was used for the meta-analysis. Result: Overall, 17 studies with 6002 study participants were included to identify risk factors of erectile dysfunction among diabetic patients. Duration of diabetes mellitus >10 years (AOR = 2.63; 95% CI 1.27, 5.43), age >40 years (AOR = 1.24; 95% CI: 1.03, 1.51), peripheral neuropathy (AOR = 2.34; 95% CI: 1.51, 10.72), no physical exercise (AOR = 1.63; 95% CI: 1.49, 1.78), testosterone level 40 years, testosterone deficiency, peripheral neuropathy, not involved in physical exercise, peripheral vascular disease, were significantly associated with increased risk of erectile dysfunction among diabetic patients Therefore, situation-based interventions and country context-specific preventive strategies should be developed to decrease the risk factors of erectile dysfunction among patients with diabetes mellitus. |
| Databáze: | OpenAIRE |
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