Thyroid and Cardiovascular Disease: A Focused Review on the Impact of Hyperthyroidism in Heart Failure
| Autor: | Kimberly O’Dell, Harris Mufti, Abdul-Razaq Adeniyi, Taiba Khan, Junhong Gui, Marc Erickson, Joseph Pendley, Rafay Khan, Juan Malpartida, Dharmendra Patel, Saif Aldeen Al-Adwan, Zarmina Mufti, Diana Alvarez, Joshua Davis, Saad Sikanderkhel |
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| Rok vydání: | 2020 |
| Předmět: |
endocrine system
medicine.medical_specialty endocrine system diseases Cardiomyopathy Heart failure Review Disease 030204 cardiovascular system & hematology Cardiovascular Hyperthyroidism 03 medical and health sciences 0302 clinical medicine Internal medicine medicine 030212 general & internal medicine Thyroid Ejection fraction business.industry medicine.disease Review article Cardiovascular physiology medicine.anatomical_structure Etiology Cardiology Cardiology and Cardiovascular Medicine business hormones hormone substitutes and hormone antagonists |
| Zdroj: | Cardiology Research |
| ISSN: | 1923-2837 1923-2829 |
| Popis: | The association between thyroid hormones and cardiovascular conditions has been well studied, specifically, the effects of hypothyroidism on cardiomyopathy, and hyperthyroidism with arrhythmias. Nonetheless, an explicit correlation between hyperthyroidism and cardiomyopathy has yet to be established. Medical databases MEDLINE and PubMed were accessed and queried as primary sources for data acquisition. Search criteria consisted of “hyperthyroidism”, “heart failure”, and “thyroid and cardiovascular system”, which allowed the retrieval of relevant and recent works. From these sources, a consensus was developed and employed to yield an updated review of the etiology of heart failure in the setting of hyperthyroidism. It is rare for patients with hyperthyroidism to remain in a chronic hyperthyroid state, making it difficult to analyze subsequent long-term effects on the cardiovascular system. Related to heart failure, some studies have demonstrated no change in ejection fraction, while others have shown an acute change along with diastolic dysfunction, with or without an underlying rhythm abnormality. Further investigation is warranted to elucidate the mechanism driving such cardiac dysfunction, and whether it is due to vascular changes, tachyarrhythmias, or myocyte remodeling and fibrosis. The intent of this review article is to improve our understanding of how a hyperthyroid state affects cardiovascular function. An enhanced understanding of the effects on cardiovascular physiology will afford physicians the ability to provide more comprehensive care in consideration of both endocrine and cardiovascular pathologies. |
| Databáze: | OpenAIRE |
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