External beam accelerated partial breast irradiation: dosimetric assessment of conformal and three different intensity modulated techniques
| Autor: | Csaba Polgár, Csilla Pesznyák, Norbert Mészáros, Tibor Major, Gábor Stelczer |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Organs at Risk
medicine.medical_treatment R895-920 Planning target volume Radiation Dosage Heart protection 030218 nuclear medicine & medical imaging Medical physics. Medical radiology. Nuclear medicine 03 medical and health sciences 0302 clinical medicine Unilateral Breast Neoplasms Humans Medicine Arc therapy Radiology Nuclear Medicine and imaging Breast External beam radiotherapy IMRT Radiation Injuries Lung business.industry Radiotherapy Planning Computer-Assisted Partial Breast Irradiation Heart Radiotherapy Dosage Spine accelerated partial breast irradiation Radiation therapy Oncology 030220 oncology & carcinogenesis Ipsilateral breast dosimetric evaluation Female Radiotherapy Intensity-Modulated Radiotherapy Conformal Three dimensional conformal radiotherapy business Nuclear medicine RapidArc Research Article |
| Zdroj: | Radiology and Oncology Radiology and Oncology, Vol 53, Iss 1, Pp 123-130 (2019) |
| ISSN: | 1581-3207 |
| DOI: | 10.2478/raon-2019-0001 |
| Popis: | Background The aim of the study was to evaluate and compare four different external beam radiotherapy techniques of accelerated partial breast irradiation (APBI) considering target coverage, dose to organs at risk and overall plan quality. The investigated techniques were three dimensional conformal radiotherapy (3D-CRT), “step and shoot” (SS) and “sliding window” (SW) intensity-modulated radiotherapy (IMRT), intensity-modulated arc therapy (RA). Patients and methods CT scans of 40 APBI patients were selected for the study. The planning objectives were set up according to the international recommendations. Homogeneity, conformity and plan quality indices were calculated from volumetric and dosimetric parameters of target volumes and organs at risk. The total monitor units and feasibility were also investigated. Results There were no significant differences in the coverage of the target volume between the techniques. The homogeneity indices of 3D-CRT, SS, SW and RA plans were 0.068, 0.074, 0.058 and 0.081, respectively. The conformation numbers were 0.60, 0.80, 0.82 and 0.89, respectively. The V50% values of the ipsilateral breast for 3D-CRT, SS, SW and RA were 47.5%, 40.2%, 39.9% and 31.6%, respectively. The average V10% and V40% values of ipsilateral lung were 13.1%, 28.1%, 28%, 36% and 2.6%, 1.9%, 1.9%, 3%, respectively. The 3D-CRT technique provided the best heart protection, especially in the low dose region. All contralateral organs received low doses. The SW technique achieved the best plan quality index (PQI). Conclusions Good target volume coverage and tolerable dose to the organs at risk are achievable with all four techniques. Taking into account all aspects, we recommend the SW IMRT technique for APBI. |
| Databáze: | OpenAIRE |
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