Cognitive impairment in obstructive sleep apnea
| Autor: | Nadia Gosselin, Marie-José Fortin, Andrée-Ann Baril, Chantal Lafond, Alex Desautels, Katia Gagnon, Jacques Montplaisir, Anne Décary, Jean-François Gagnon |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Neuroimaging Comorbidity Disorders of Excessive Somnolence Executive Function Physical medicine and rehabilitation Risk Factors medicine Dementia Humans Attention Continuous positive airway pressure Hypoxia Episodic memory Evoked Potentials Aged Memory Disorders Sleep Apnea Obstructive Continuous Positive Airway Pressure Working memory business.industry Snoring Neuropsychology Cognition Electroencephalography General Medicine Middle Aged Executive functions medicine.disease respiratory tract diseases Obstructive sleep apnea Physical therapy Sleep Deprivation Brain Damage Chronic Female business Cognition Disorders Psychomotor Performance |
| Zdroj: | Pathologie-biologie. 62(5) |
| ISSN: | 1768-3114 |
| Popis: | Obstructive sleep apnea (OSA) is characterised by repetitive cessation or reduction of airflow due to upper airway obstructions. These respiratory events lead to chronic sleep fragmentation and intermittent hypoxemia. Several studies have shown that OSA is associated with daytime sleepiness and cognitive dysfunctions, characterized by impairments of attention, episodic memory, working memory, and executive functions. This paper reviews the cognitive profile of adults with OSA and discusses the relative role of altered sleep and hypoxemia in the aetiology of these cognitive deficits. Markers of cognitive dysfunctions such as those measured with waking electroencephalography and neuroimaging are also presented. The effects of continuous positive airway pressure (CPAP) on cognitive functioning and the possibility of permanent brain damage associated with OSA are also discussed. Finally, this paper reviews the evidence suggesting that OSA is a risk factor for developing mild cognitive impairment and dementia in the aging population and stresses the importance of its early diagnosis and treatment. |
| Databáze: | OpenAIRE |
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