Ten years disease-free survival after solitary brain metastasis from breast cancer
| Autor: | Ursula Nestle, K. Walter, Klaus Schnabel, Carsten Nieder |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Cancer Research
medicine.medical_specialty Antineoplastic Agents Hormonal medicine.medical_treatment Breast Neoplasms Disease-Free Survival Metastasis Breast cancer Carcinoma Humans Medicine Lymph node Brain Neoplasms business.industry General Medicine Middle Aged medicine.disease Combined Modality Therapy Surgery Supraclavicular lymph nodes Radiation therapy medicine.anatomical_structure Oncology Female business Tamoxifen medicine.drug Brain metastasis |
| Zdroj: | Journal of Cancer Research and Clinical Oncology. 122:570-572 |
| ISSN: | 1432-1335 0171-5216 |
| Popis: | The unique case of a 51-year-old woman who developed a solitary brain metastasis as the first site of systemic disease 11 months after a total mastectomy for an undifferentiated infiltrating ductal carcinoma of her right breast is described. After surgery for the pT2pN0 carcinoma, the patient received radiotherapy of the internal mammary and supraclavicular lymph nodes. The brain metastasis was treated with surgery and adjuvant whole-brain radiotherapy to a total dose of 30 Gy in December 1984 and January 1985. Afterwards a hormonal treatment with tamoxifen was initiated, which still continues. Since then no further distant or lymph node metastases have developed. The patient is under regular after-care and undergoes various apparative examinations every 6 months. She is generally well and suffers only from a postoperatively persistent hemianopsia. This is the first case in which a disease-free survival for more than 10 years after brain metastases from breast cancer has been reported. It illustrates the specific biological behaviour of this tumour type and the chance of achieving long-term survival in very selected cases. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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