Comparative data analsysis of two multi-drug resistant homoserine lactone and rhamnolipid producing Pseudomonas aeruginosa from diabetic foot infected patient
| Autor: | Kodiveri Muthukaliannan Gothandam, E. Padmavathi, Sankaranarayanan Gomathinayagam, Nalini Easwaran, Manoharan Shankar, Karthikeyan Sivashanmugam, Gowri Sankar, Prakhar Srivastava |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Homoserine
Virulence Diabetic foot ulcer Biology medicine.disease_cause lcsh:Computer applications to medicine. Medical informatics Microbiology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Biochemistry Genetics and Molecular Biology medicine Homoserine lactone lcsh:Science (General) 030304 developmental biology Whole genome sequencing 0303 health sciences Multidisciplinary Efflux pump Pseudomonas aeruginosa Biofilm Rhamnolipid Quorum sensing chemistry lcsh:R858-859.7 Nanopore sequencing 030217 neurology & neurosurgery lcsh:Q1-390 |
| Zdroj: | Data in Brief, Vol 32, Iss, Pp 106071-(2020) Data in Brief |
| ISSN: | 2352-3409 |
| Popis: | Pseudomonas aeruginosa generally forms strong biofilm during chronic condition of wound. The whole mechanism of biofilm formation works in tandem with quorum sensing circuit of the organism in order to produce virulence. Here we report the draft genome sequence of two diabetic foot ulcer Pseudomonas aeruginosa isolates (VIT PC 7 and VIT PC 9) displaying homoserine lactone, rhamnolipid producing, biofilm phenotype and antibiotic resistance genes related to carbapenem, aminoglycoside, beta- lactamase and tetracycline resistance. The whole genome sequencing library was prepared according to the Oxford Nanopore's SQK-LSK108 kit protocol on Oxford Nanopore's Minion platform. The 7.1 Mb and 6.3-Mb draft genome sequence with GC content of 65.8% and 66.4% respectively provides insight into their resistance mechanism and virulence factors. |
| Databáze: | OpenAIRE |
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