Graham-Little Piccardi Lassueur Syndrome: case report

Autor: Ernani Siegmann Duvelius, Renata Elise Tonoli, Giselle Martins Pinto, Raquel Bissacotti Steglich, Fernanda Melo Müller, Isabelle Maffei Guarenti
Rok vydání: 2012
Předmět:
Zdroj: Anais Brasileiros de Dermatologia. 87:775-777
ISSN: 0365-0596
DOI: 10.1590/s0365-05962012000500019
Popis: A 33-year-old woman presented with a 3-year history of progressive alopecia of the scalp. Past treatment with hydroxicloroquine did not show improvement. Physical examination revealed multiple areas of alopecia with atrophic aspect of the scalp, and axillary and pubic hypotrichosis. Dermoscopy showed hyperkeratosis and accentuation of follicular ostia. Anatomopathological examination revealed decrease in the number of hair follicles, upper perifollicular infiltrate and areas with fibrosis. The Piccardi-Lassueur-Graham-Little syndrome is a rare disorder, characterized by the triad of multifocal scarring alopecia of the scalp, keratotic follicular eruption and hypotrichosis of axillary and pubic regions. Management is a challenge and many medications tried have controversial results. We report a case of this rare syndrome which improved with corticoids.
Databáze: OpenAIRE