Influence of body mass index on revision rates after primary total knee arthroplasty
| Autor: | Pierre Hoffmeyer, Matthieu Zingg, Hermès Howard Miozzari, Anne Lübbeke, Daniel Fritschy |
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| Rok vydání: | 2015 |
| Předmět: |
musculoskeletal diseases
Male Reoperation medicine.medical_specialty Obesity/complications/surgery Kaplan-Meier Estimate Overweight Body Mass Index Cohort Studies 03 medical and health sciences 0302 clinical medicine Humans Medicine Orthopedics and Sports Medicine Obesity Prospective Studies 030212 general & internal medicine Arthroplasty Replacement Knee Prospective cohort study Survival analysis Aged Proportional Hazards Models 030222 orthopedics ddc:617 Overweight/complications/surgery business.industry Proportional hazards model Hazard ratio Middle Aged musculoskeletal system Confidence interval Surgery Regression Analysis Female medicine.symptom business Body mass index Follow-Up Studies Cohort study |
| Zdroj: | International Orthopaedics, Vol. 40, No 4 (2016) pp. 723-9 |
| ISSN: | 1432-5195 0341-2695 |
| Popis: | Studies demonstrate that revision rates after primary total knee arthroplasty (TKA) tend to be higher in obese patients. However, the existence of a body mass index (BMI) threshold remains unexplored. We conducted a prospective cohort study of 2442 primary TKAs in 2035 patients (69.1 % women; mean age 72 years; mean follow-up 93 months, range 38–203). We evaluated the influence of BMI in five categories on all-cause revision after TKA using incidence rates (IR), hazard ratios (HR), and Kaplan–Meier survival analysis. Adjustment for baseline imbalances was performed using Cox regression analysis. Over the study period, 71 revisions occurred. Revision rates were 3.2 cases/1000 patient-years for patients of normal weight, 3.4/1000 for overweight patients and 3.0/1000 for patients classified as obese class I. At BMI ≥ 35, a significant increase in revision was noted. Comparing BMI ≥ 35 vs. < 35, there were 6.4 vs. 3.2 /1000. Crude HR was 2.0 [95 % confidence interval (CI) 1.2–3.3, p = 0.009], and the adjusted HR was 2.1 (95 % CI 1.2–3.6, p = 0.008). All-cause revision rates after primary TKA doubled in patients with a BMI of 35 but were similar in those with a BMI |
| Databáze: | OpenAIRE |
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