Placental chemical elements concentration in small fetuses and its relationship with Doppler markers of placental function

Autor: Daniel Cuadras, P. Ferrer, M. Muniesa, Gómez-Roig, M. Cantallops, E. Mazarico, R. Pascal, Eduard Gratacós, M. Falcon, M. Arraez
Rok vydání: 2021
Předmět:
Placenta
Adult
Male
0301 basic medicine
chemistry.chemical_element
Gestational Age
Ultrasonography
Prenatal
Cohort Studies
Andrology
03 medical and health sciences
Fetus
0302 clinical medicine
Pregnancy
medicine.artery
medicine
Humans
Doppler markers
Prospective Studies
Uterine artery
Maternal-Fetal Exchange
reproductive and urinary physiology
Placental function
Cadmium
Fetal Growth Retardation
030219 obstetrics & reproductive medicine
Magnesium
Spectrophotometry
Atomic
Infant
Newborn
Obstetrics and Gynecology
Ultrasonography
Doppler
Umbilical artery
Elements
Placental Insufficiency
Small fetuses
female genital diseases and pregnancy complications
030104 developmental biology
medicine.anatomical_structure
Element concentration
Fetal Weight
Reproductive Medicine
chemistry
Infant
Small for Gestational Age
Thallium
Female
Selenium
Developmental Biology
Zdroj: Placenta
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
ISSN: 0143-4004
DOI: 10.1016/j.placenta.2021.05.001
Popis: INTRODUCTION: In this study, we aimed at quantifying placental concentrations of 22 chemical elements in small fetuses (SGA) as compared with normally grown fetuses (AGA), and to assess the relationship with Doppler markers of placental function. METHODS: Prospective cohort study, including 71 SGA fetuses (estimated fetal weight 10th percentile), recruited in the third trimester of gestation. The placental concentration of 22 chemical elements was determined by inductively coupled plasma optical emission spectrophotometer (ICP-OES, ICAP 6500 Duo Thermo): aluminum (Al), beryllium (Be), bismuth (Bi), calcium (Ca), cadmium (Cd), cobalt (Co), chrome (Cr), copper (Cu), magnesium (Mg), manganese (Mn), molybdenum (Mo), nickel (Ni), phosphorus (P), lead (Pb), rubidium (Rb), sulfur (S), strontium (Sr), titanium (Ti), thallium (Tl), antimony (Sb), selenium (Se), and zinc (Zn). Placental function was assessed by measuring the following fetal-maternal parameters: Uterine artery Pulsatility Index (UtA PI), Umbilical artery Pulsatility Index (UA PI) and Middle Cerebral artery Pulsatility Index (MCA PI). The association between the chemical elements concentration and study group and the association with Doppler measures were evaluated. RESULTS: SGA was associated with significantly (p
Databáze: OpenAIRE
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