Amantadine Small-Particle Aerosol: Generation and Delivery to Man
| Autor: | Vernon Knight, Samuel Z. Wilson, Rebecca Moore, Edgar W. Larson |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Aerosols
Oral dose Time Factors Inhalation business.industry Amantadine Influenza a respiratory system Pharmacology complex mixtures General Biochemistry Genetics and Molecular Biology Aerosol Clinical study Mice Anesthesia Aerosol generator Influenza Human Animals Humans Technology Pharmaceutical Medicine Small particles business medicine.drug |
| Zdroj: | Experimental Biology and Medicine. 161:350-354 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-161-40551 |
| Popis: | SummaryAn aerosol generator suitable for administration of a small-particle aerosol of amantadine for treatment of influenza A infection in man is described. As currently operated, the usual daily recommended oral dose of amantadine of 120 to 200 mg can be given in 8 to 10 hr of inhalation of the aerosol. Limited clinical study indicates the safety and probable efficacy of this method of treatment. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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