Assessment of the myocardial perfusion pattern in patients with multivessel coronary artery disease
| Autor: | Sally A. Kane, A-Hamid Hakki, Bernard L. Segal, Angelo Amenta, Abdulmassih S. Iskandrian |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Adult
Male medicine.medical_specialty Collateral Circulation Infarction Coronary Disease Coronary artery disease Electrocardiography Coronary circulation Heart Rate Coronary Circulation Internal medicine Heart rate Humans Medicine cardiovascular diseases Thallium Radionuclide Imaging Aged Radioisotopes medicine.diagnostic_test business.industry Middle Aged medicine.disease Collateral circulation Perfusion medicine.anatomical_structure Exercise Test cardiovascular system Cardiology Female Radiology Cardiology and Cardiovascular Medicine business Artery |
| Zdroj: | American Heart Journal. 106:1089-1096 |
| ISSN: | 0002-8703 |
| DOI: | 10.1016/0002-8703(83)90657-9 |
| Popis: | We studied 42 symptomatic patients with coronary artery disease involving two or three vessels using exercise thallium-201 myocardial scintigraphy. Qualitative analysis of the images predicted multivessel disease in 75% of the patients with two-vessel disease and in 82% of the patients with three-vessel disease. Quantitative analysis of the size of the perfusion defect indicated that approximately 40% of the left ventricular perimeter showed abnormal perfusion pattern during stress in these patients, and there was no significant difference in the size of the defect in patients with two-vessel disease or three-vessel disease (41 +/- 17% vs 42 +/- 14%, respectively, mean +/- SD). The exercise heart rate, exercise ECG response, and severity of narrowing did not correlate with the size of the perfusion defect. Patients with anterior infarction had larger defects in the distribution of the left anterior descending artery than those without infarction. Collaterals offered partial protection during exercise only when they were not jeopardized. This study confirms the value of qualitative analysis of exercise thallium-201 imaging in predicting multivessel disease, and describes a simple method of assessing the extent of perfusion abnormalities during stress in patients with multivessel disease. The results may be important in patient management and prognosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|