Breast-conserving surgery with radiation therapy for operable mammary carcinoma: a 25-year experience

Autor: C. Bressac, J. M. Spitalier, J. M. Kurtz, J. Seigle, Yves Ayme, R. Amalric, D. Hans, Santamaria F, F. Robert, J. F. Pollet, F. Amalric, J. M. Brandone, Henri Brandone, J. Gambarelli
Rok vydání: 1986
Předmět:
Zdroj: World journal of surgery. 10(6)
ISSN: 0364-2313
Popis: This article describes the long-term results of breast-conserving treatment for 1,133 consecutive patients with operable mammary cancer treated from 1961 to 1979 by limited surgery followed by curative irradiation. Follow-up ranged from 5 to 23 years. The percentage of patients (clinical stages I and II combined) alive and well at 5, 10, and 15 years was 86%, 80%, and 62%, respectively. The percentage of cured patients having retained their treated breast was 85% at 15 years. One hundred forty-nine patients (13.2%) developed recurrence in the treated breast and 67 patients (5.9%) recurred in the axilla, most commonly in conjunction with breast failure. Ninety-one percent of the local-regional recurrences were operable, and the 5-year survival following salvage surgery was 61%. The cosmetic results of therapy were judged to be good or excellent in 70% of patients at 15 years, with 2–4% of the patients having unacceptable results. It is concluded that breast-conserving surgery followed by radiation therapy for clinical stages I and II results in survival rates equivalent to those achieved by primary radical surgery. This method allows reliable local-regional disease control while permitting the majority of patients to retain their breasts in an esthetically acceptable condition. In contrast to recurrences after radical surgery, local-regional recurrences after conservative therapy can be successfully treated by further surgery.
Databáze: OpenAIRE
Externí odkaz: