Effects of Preoperative Enteral Nutrition on Postoperative Recent Nutritional Status in Patients with Siewert II and III Adenocarcinoma of Esophagogastric Junction after Neoadjuvant Chemoradiotherapy

Autor:	Bin Yu, Liqiao Fan, Yuan Tian, Bibo Tan, Yong Li, Peigang Yang, Qun Zhao
Rok vydání:	2018
Předmět:	0301 basic medicine Adult Male Cancer Research medicine.medical_specialty Esophageal Neoplasms medicine.medical_treatment Medicine (miscellaneous) Nutritional Status Adenocarcinoma Gastroenterology law.invention 03 medical and health sciences 0302 clinical medicine Enteral Nutrition Randomized controlled trial law Risk Factors Internal medicine Medicine Humans In patient Esophagogastric junction Neoadjuvant therapy Aged 030109 nutrition & dietetics Nutrition and Dietetics business.industry Nutritional status Chemoradiotherapy Middle Aged medicine.disease Neoadjuvant Therapy Parenteral nutrition Oncology 030220 oncology & carcinogenesis Female Esophagogastric Junction business
Zdroj:	Nutrition and cancer. 70(6)
ISSN:	1532-7914
Popis:	To study the effects of preoperative enteral nutrition (EN) on postoperative recent nutritional status (PRNS) in patients with Siewert II and III adenocarcinomas of esophagogastric junction (AEG) after neoadjuvant chemoradiotherapy (NCRT).A total of 66 patients with resectable AEG (Siewert II and III) were randomly divided into two groups. The trial group accepted oral nutrition supplementation (ONS) for 7 days before surgery while the control not.Nutrition indexes were higher in trial group after surgery whereas the opposite was true for the diamine oxidase (DAO) and d-lactate (P 0.05). The rate of malnutrition and nutritional risk became lower in trial group on the 8th day after surgery (P 0.05). Injury levels of intestinal mucosa were more severe among control group. The recent prognosis was better in trial group. For patients with or without nutritional risks at admission, the PRNS and recent prognosis were improved by preoperative EN. Logistic regression analysis suggested that preoperative EN could be an independent protective factor of PRNS.Preoperative EN may improve the PRNS and recent prognosis of patients with Siewert II and III AEG after NCRT.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5f92af836fd3220b383440485f6a3b https://pubmed.ncbi.nlm.nih.gov/30273016 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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